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<p style="text-align:left; margin:0pt 0pt 0.0001pt"><span style="font-size:10.5pt"><span style="font-family:Calibri"><span style="font-size:9.0000pt"><span style="background:#ffffff"><span style="font-family:'Microsoft YaHei UI'"><span style="color:#000000"><span style="letter-spacing:0.6000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="Microsoft YaHei UI">丙通沙（吉三代）</font></span></span></span></span></span></span></span><span style="font-size:9.0000pt"><span style="background:#ffffff"><span style="font-family:'Microsoft YaHei UI'"><span style="color:#000000"><span style="letter-spacing:0.6000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="Microsoft YaHei UI">主要成分为</font>NS5B抑制剂索磷布韦和NS5A抑制剂维帕他韦，不含蛋白酶抑制剂。</span></span></span></span></span></span></span></span></span></p>

<p style="text-align:left; margin:0pt 0pt 0.0001pt"> </p>

<p style="text-align:left; margin:0pt 0pt 0.0001pt"><span style="font-size:10.5pt"><span style="font-family:Calibri"><span style="font-size:9.0000pt"><span style="background:#ffffff"><span style="font-family:'Microsoft YaHei UI'"><span style="color:#000000"><span style="letter-spacing:0.6000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="Microsoft YaHei UI">美国</font>FDA报告称，使用含</span></span></span></span></span></span></span><span style="font-size:9.0000pt"><span style="background:#ffffff"><span style="font-family:'Microsoft YaHei UI'"><span style="color:#000000"><span style="letter-spacing:0.6000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="Microsoft YaHei UI">蛋白酶抑制剂的药物治疗中度至重度肝功能损害（</font><font face="Microsoft YaHei UI">Child-Pugh B或C）的慢性丙型肝炎患者，会导致肝功能恶化，甚至肝功能衰竭。</font></span></span></span></span></span></span></span></span></span></p>

<p style="text-align:left; margin:0pt 0pt 0.0001pt"> </p>

<p style="text-align:left; margin:0pt 0pt 0.0001pt"><span style="font-size:10.5pt"><span style="font-family:Calibri"><span style="font-size:9.0000pt"><span style="background:#ffffff"><span style="font-family:'Microsoft YaHei UI'"><span style="color:#000000"><span style="letter-spacing:0.6000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="Microsoft YaHei UI">中国丙肝指南也明确指出，蛋白酶抑制剂在严重肝损伤患者中的不良反应发生率很高，含蛋白酶抑制剂的泛基因治疗方案禁用于失代偿性肝硬化的丙肝患者。</font></span></span></span></span></span></span></span></span></span></p>

<p style="text-align:left; margin:0pt 0pt 0.0001pt"> </p>

<p style="text-align:left; margin:0pt 0pt 0.0001pt"><span style="font-size:10.5pt"><span style="font-family:Calibri"><span style="font-size:9.0000pt"><span style="background:#ffffff"><span style="font-family:'Microsoft YaHei UI'"><span style="color:#000000"><span style="letter-spacing:0.6000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="Microsoft YaHei UI">丙通沙可规避发生肝脏不良事件的风险，可用于任何程度肝损伤的丙肝患者。</font></span></span></span></span></span></span></span></span></span></p>

<p style="text-align:left; margin:0pt 0pt 0.0001pt"><span style="font-size:10.5pt"><span style="font-family:Calibri"><span style="font-size:9.0000pt"><span style="background:#ffffff"><span style="font-family:'Microsoft YaHei UI'"><span style="color:#000000"><span style="letter-spacing:0.6000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="Microsoft YaHei UI">另外丙肝患者并发慢性肾脏病的风险远远高于普通人群，</font><font face="Microsoft YaHei UI">20～64岁和65岁以上人群的并发比例分别为8.5%和26.5%</font></span></span></span></span></span></span></span><span style="font-size:9.0000pt"><span style="background:#ffffff"><span style="font-family:'Microsoft YaHei UI'"><span style="color:#000000"><span style="letter-spacing:0.6000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="Microsoft YaHei UI">。丙通沙被国家药品监督管理局</font><font face="Microsoft YaHei UI">(NMPA)批准用于合并有任何程度肾功能损害的丙肝患者，且无需调整剂量。对于失代偿肝硬化合并严重肾功能损害的丙肝患者，丙通沙是可选择的</font></span></span></span></span></span></span></span><span style="font-size:9.0000pt"><span style="background:#ffffff"><span style="font-family:'Microsoft YaHei UI'"><span style="color:#000000"><span style="letter-spacing:0.6000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="Microsoft YaHei UI">优秀</font></span></span></span></span></span></span></span><span style="font-size:9.0000pt"><span style="background:#ffffff"><span style="font-family:'Microsoft YaHei UI'"><span style="color:#000000"><span style="letter-spacing:0.6000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="Microsoft YaHei UI">方案。</font></span></span></span></span></span></span></span></span></span></p>

<p style="text-align:left; margin:0pt 0pt 0.0001pt"> </p>

<p>丙通沙，就是印度吉三代</p>

<p>原厂的吉三代价格昂贵，让很多丙肝患者望而却步，印度产的<span style="color:#3498db;"><u><strong>吉三代</strong></u></span>，效果和美国原厂一致，价格却十分低廉，因此成为绝大多数患者的不二之选。</p>

<p>如果您有关于丙肝治疗，<font color="#3498db"><b><u>吉三代</u></b></font>方面的疑问，可直接致电鲸人医疗专家热线：18515676770/15321833786，<a href="http://kft.zoosnet.net/LR/Chatpre.aspx?id=KFT36340607&lng=cn" onclick="window.open(this.href, '', 'resizable=no,status=no,location=no,toolbar=no,menubar=no,fullscreen=no,scrollbars=no,dependent=no'); return false;"><span style="color:#ffffff;"><span style="background-color:#f39c12;">立即咨询</span></span></a></p>

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