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<p style="margin:0pt 0pt 0.0001pt; text-align:justify"><span style="font-size:10.5pt"><span style="font-family:Calibri">                                                                           <span style="font-size:12.0000pt"><span style="font-family:微软雅黑"><font face="微软雅黑">索拉菲尼（多吉美）的用法用量及中文说明</font></span></span></span></span></p>

<p style="margin:0pt 0pt 0.0001pt; text-align:justify"> </p>

<p style="margin:0pt 0pt 0.0001pt; text-align:justify"><span style="font-size:10.5pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="font-family:微软雅黑"><font face="微软雅黑">索拉菲尼（多吉美）属于肝癌的一类靶向药，鲸人健康带您来了解一下索拉菲尼（多吉美）的用法用量。</font></span></span></span></span></p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"> </p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"><span style="font-size:12pt"><span style="background:#ffffff"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#2c2f34"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal">1、治疗不能手术的晚期肾细胞癌。</span></span></span></span></span></span></span></span></span></span></p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"> </p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"><span style="font-size:12pt"><span style="background:#ffffff"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#2c2f34"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal">2、治疗无法手术或远处转移的肝细胞癌。</span></span></span></span></span></span></span></span></span></span></p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"><span style="font-size:12pt"><span style="background:#ffffff"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#2c2f34"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">目前缺乏在晚期肝细胞癌患者中索拉非尼与介入治疗如肝动脉栓塞化疗（</font>TACE）比较的随机对照临床研究数据，因此 尚不能明确本品相对介入治疗的优劣，也不能明确对既往接受过介入治疗后患者使用索拉非尼是否有益。建议医生根据患者具体情况综合考虑，选择适宜治疗手段。</span></span></span></span></span></span></span></span></span></span></p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"> </p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"><span style="font-size:12pt"><span style="background:#ffffff"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#2c2f34"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal">3、<font face="微软雅黑">治疗局部复发或转移的进展性的放射性碘难治性分化型甲状腺癌。</font></span></span></span></span></span></span></span></span></span></span></p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"> </p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"><span style="font-size:12pt"><span style="background:#ffffff"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#2c2f34"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">服用方法是：</font></span></span></span></span></span></span></span><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#2c2f34"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">口服，以一杯温开水吞服。</font></span></span></span></span></span></span></span></span></span></span></p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"><span style="font-size:12pt"><span style="background:#ffffff"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#2c2f34"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">推荐服用索拉非尼的剂量为每次</font> 0.4g（2×0.2g）、每日两次，空腹或伴低脂、中脂饮食服用。</span></span></span></span></span></span></span></span></span></span></p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"> </p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"><span style="font-size:12pt"><span style="background:#ffffff"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#2c2f34"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">鲸人健康在此提醒您</font>:如在服用过程中副作用过大，请及时就医，酌情减量服用</span></span></span></span></span></span></span></span></span></span></p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"> </p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"><span style="font-size:12pt"><span style="background:#ffffff"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#2c2f34"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">如果您有关于靶向药索拉非尼</font>,仑伐替尼方面的疑问，可直接致电鲸人健康</span></span></span></span></span></span></span></span></span></span></p>

<p class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:9.4000pt; padding:0pt 0pt 0pt 0pt ; margin:5pt 0pt; text-align:left"><span style="font-size:12pt"><span style="background:#ffffff"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#2c2f34"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">顾问热线：</font></span></span></span></span><span style="color:#3498db;"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><strong>18515676770/15321833786</strong></span></span></span></span><span style="color:#2c2f34"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal">，<a href="http://kft.zoosnet.net/LR/Chatpre.aspx?id=KFT36340607&lng=cn"><strong><span style="background-color:#f1c40f;">立即咨询</span></strong></a></span></span></span></span></span></span></span></span></span></span></p>

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